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KMID : 1214920140200010031
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Soonchunhyang Medical Science
2014 Volume.20 No. 1 p.31 ~ p.34
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Rosai-Dorfman Disease Combined with Aortic Vasculitis, Arrhythmia, and Valvular Heart Disease
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Kim Shin-Il
Han Ji-Young
Park Young-Hoon
Lim Joo-Han
Lee Moon-Hee
Kim Chul-Soo
Yi Hyeon-Gyu
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Abstract
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Rosai-Dorfman disease (RDD) is a rare and benign self-limited disorder with pathologic feature of the lymph node sinuses expanded by a proliferation of distinctive histiocytes. The most often involving site is bilateral cervical lymphadenopathy, followed by the skin and soft tissue. Treatment options, including steroid, chemotherapy, radiotherapy and debulking surgery depend on the symptoms or the extent and localization of the lesions. We encountered a very rare case of RDD at the skin lesions, particularly combined with aortic vasculitis, arrhythmia, and valvular heart disease.
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KEYWORD
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Rosai-Dorfman disease, Vasculitis, Cardiac arrhythmia, Heart valve diseases, Prednisolone, Methotrexate
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